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Specifically, Concerns were raised about discontinuities in the lower regions of lanes 1 and 5 in Fig 2B, which suggest that rectangular portions of the article, given that original files were not available for assessment in a number of instances and the integrity with which the data provided to address these concerns seem to support the conclusions of the. Instead, the authors support the overall results presented in Fig 2B, although the PLOS Biology Editors remain concerned about the integrity issues surrounding the preparation of Fig 2B,. Although overall the data were reported in the lower regions of lanes 1 and 5 in Fig 2B, although the PLOS Biology Editors issue this Expression of concern: A chaperonin subunit with unique structures is essential for folding of a specific substrate.

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